Hypotensive action of human renin inhibitor KRI-1314 in the common marmoset.
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چکیده
منابع مشابه
DIETARY SALT REDUCTION POTENTIATES THE ACTION OF HYPOTENSIVE DRUGS
Hypertension is a common health problem. Hypotensive drugs and low salt diet are used in its treatment. This study was designed to compare the effectiveness of a low-salt diet and drug therapy in the treatment of arterial hypertension. A total of 256 randomly selected patients with essential hypertension consulting the Non-contagious Diseases Clinic in Shahreza, Isfahan, Iran, were included...
متن کاملEffects of a specific and long-acting renin inhibitor in the marmoset.
Inhibition of renin was induced in conscious marmosets with CGP 29 287, Z-Arg-Arg-Pro-Phe-His-Sta-Ile-His-Lys (Boc)-OMe, a renin inhibitor with a prolonged duration of action. In vitro, CGP 29 287 is a potent inhibitor of primate plasma renin (inhibitory concentration, 50%: human = 1 X 10(-9) M; marmoset = 5 X 10(-9) M) and less potent against dog (2 X 10(-7) M) or rat (3 X 10(-5) M) plasma ren...
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15 صفحه اولReport on Round Table on renin suppression and the hypotensive action of beta-adrenergic-blocking drugs.
ROBERTSON: We have this morning rather a large Round Table, with ten speakers, all of whom have been promised that they will get at least one chance to speak. Also quite a number of people in the audience have indicated to me that they wish to join in. Unfortunately, we are limited to 1 h. It is my job as Chairman to try to reconcile some of these obviously irreconcilable objectives and we shal...
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ژورنال
عنوان ژورنال: Folia Pharmacologica Japonica
سال: 1994
ISSN: 0015-5691,1347-8397
DOI: 10.1254/fpj.103.161